Couple

MY CONFIDENCE:
Understanding my condition.

All photos on this site are actor portrayals.

Cervical dystonia (CD) affects thousands of people. Symptom recognition often represents the first step toward treatment.

CD, also called spasmodic torticollis, is a neurological movement disorder that causes the muscles in your neck to contract (tighten) involuntarily. This muscle tightening can cause you to hold your head and neck in painful, abnormal positions. These painful, abnormal head positions can cause discomfort and challenges in your everyday life.

MOST COMMON POSTURES ASSOCIATED WITH CD

Illustration of a woman looking to the right

TORTICOLLIS
(rotation)

Illustration of a woman looking up

RETROCOLLIS
(extension)

Illustration of a woman tilting her head to the left

LATEROCOLLIS
(lateral tilt)

Illustration of a woman looking down

ANTEROCOLLIS
(flexion)

CD SYMPTOMS INCLUDE:

  • Abnormal and painful turning of head and neck
  • Increasing neck muscle tightness or spasms
  • Neck pain
  • Uncomfortable pulling in the neck
  • Tremors of the head and neck
  • Limited range of motion

PAIN IS A COMMON COMPLAINT OF MOST PATIENTS WITH CD

Graph representing 75% of CD patients suffering from neck pain

Up to 75% of CD patients suffer from neck pain


Icons of people with 7 of 10 colored blue

Nearly 7 of 10 patients say the pain is moderate to severe

CD pain may interfere with your work and social life*

Illustration of a man working on a computer

OCCUPATIONAL DISABILITY

Illustration of a woman frowning with a group of people behind her in the distance

SOCIAL ISOLATION

*There are no studies showing that treating cervical dystonia affects specific outcomes on this page.

WHAT CAUSES CD?

Normally, your brain sends chemical signals to your head and neck muscles to keep their movements smooth and controlled. In patients with CD, these signals work improperly. When acetylcholine, one of the chemical signals, is released at above-normal amounts, it causes muscles to be tense and overactive.

In some cases of CD, causes can be linked to neck, head, and shoulder injuries, and certain drugs.

While the exact cause is not clear, research is still being conducted to explore the factors that can contribute to CD.

Why MYOBLOC?

IMPORTANT SAFETY INFORMATION

What is MYOBLOC?

MYOBLOC is a prescription medicine used in adults that is injected into:

  • muscles and used to treat the abnormal head position and neck pain that happens with cervical dystonia (CD).
  • glands that make saliva and is used to treat long-lasting (chronic) drooling (sialorrhea).

It is not known whether MYOBLOC is safe or effective in children.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MYOBLOC?

MYOBLOC may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems after treatment with MYOBLOC:

  • Problems swallowing, speaking, or breathing. These problems can happen hours to weeks after an injection of MYOBLOC if the muscles that you use to breathe and swallow become weak after the injection. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with MYOBLOC.
    • People with certain breathing problems may need to use muscles in their neck to help them breathe. These people may be at greater risk for serious breathing problems with MYOBLOC.
    • Swallowing problems may last for several months. People who cannot swallow well may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving MYOBLOC have the highest risk of getting these problems.
  • Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body; trouble saying words clearly (dysarthria); double vision; loss of bladder control; blurred vision and drooping eyelids; trouble breathing; hoarseness or change or loss of voice (dysphonia); trouble swallowing (dysphagia).

These symptoms can happen hours to weeks after you receive an injection of MYOBLOC.

These problems could make it unsafe for you to drive a car or do other dangerous activities.

Do not receive MYOBLOC if you:

  • are allergic to MYOBLOC or any of the ingredients in MYOBLOC.
  • had an allergic reaction to any other botulinum toxin product such as BOTOX®, BOTOX® Cosmetic (onabotulinumtoxinA), DYSPORT® (abobotulinumtoxinA), or XEOMIN® (incobotulinumtoxinA).
  • have a skin infection at the planned injection site.

Before receiving MYOBLOC, tell your doctor about all your medical conditions, including if you have:

disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig’s disease], myasthenia gravis or Lambert-Eaton syndrome); had any side effect from any botulinum toxin product in the past; a breathing problem, such as asthma or emphysema; a history of swallowing problems or inhaling food or fluid into your lungs (aspiration); bleeding problems; drooping eyelids; plans to have surgery; had surgery on your face.

Tell your doctor if you:

  • are pregnant or plan to become pregnant. It is not known if MYOBLOC can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if MYOBLOC passes into breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Talk to your doctor before you take any new medicine after you receive MYOBLOC.

Using MYOBLOC with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received MYOBLOC in the past. Especially tell your doctor if you: have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as BOTOX®, BOTOX® Cosmetic (onabotulinumtoxinA), DYSPORT® (abobotulinumtoxinA), or XEOMIN® (incobotulinumtoxinA) in the past. Be sure your doctor knows exactly which product you received; have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine.

What should I avoid while receiving MYOBLOC?

MYOBLOC may cause loss of strength or general muscle weakness or vision problems within hours to weeks of receiving MYOBLOC. If this happens, do not drive a car, operate machinery or do other dangerous activities.

What are the possible side effects of MYOBLOC?

MYOBLOC can cause serious side effects including:

  • allergic reactions. Symptoms of an allergic reaction to MYOBLOC may include: itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing, or trouble breathing, or if you get dizzy or faint.

The most common side effects of MYOBLOC in people with cervical dystonia include dry mouth; injection site discomfort or pain; trouble swallowing (dysphagia); headache.

The most common side effects of MYOBLOC in people with sialorrhea include dry mouth and trouble swallowing (dysphagia).

>These are not all the possible side effects of MYOBLOC. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Medication Guide for additional information and talk with your healthcare provider.

IMPORTANT SAFETY INFORMATION

What is MYOBLOC?

MYOBLOC is a prescription medicine used in adults that is injected into:

  • muscles and used to treat the abnormal head position and neck pain that happens with cervical dystonia (CD).
  • glands that make saliva and is used to treat long-lasting (chronic) drooling (sialorrhea).

It is not known whether MYOBLOC is safe or effective in children.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about MYOBLOC?

MYOBLOC may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems after treatment with MYOBLOC:

  • Problems swallowing, speaking, or breathing. These problems can happen hours to weeks after an injection of MYOBLOC if the muscles that you use to breathe and swallow become weak after the injection. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with MYOBLOC.
    • People with certain breathing problems may need to use muscles in their neck to help them breathe. These people may be at greater risk for serious breathing problems with MYOBLOC.
    • Swallowing problems may last for several months. People who cannot swallow well may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving MYOBLOC have the highest risk of getting these problems.
  • Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body; trouble saying words clearly (dysarthria); double vision; loss of bladder control; blurred vision and drooping eyelids; trouble breathing; hoarseness or change or loss of voice (dysphonia); trouble swallowing (dysphagia).

These symptoms can happen hours to weeks after you receive an injection of MYOBLOC.

These problems could make it unsafe for you to drive a car or do other dangerous activities.

Do not receive MYOBLOC if you:

  • are allergic to MYOBLOC or any of the ingredients in MYOBLOC.
  • had an allergic reaction to any other botulinum toxin product such as BOTOX®, BOTOX® Cosmetic (onabotulinumtoxinA), DYSPORT® (abobotulinumtoxinA), or XEOMIN® (incobotulinumtoxinA).
  • have a skin infection at the planned injection site.

Before receiving MYOBLOC, tell your doctor about all your medical conditions, including if you have:

disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig’s disease], myasthenia gravis or Lambert-Eaton syndrome); had any side effect from any botulinum toxin product in the past; a breathing problem, such as asthma or emphysema; a history of swallowing problems or inhaling food or fluid into your lungs (aspiration); bleeding problems; drooping eyelids; plans to have surgery; had surgery on your face.

Tell your doctor if you:

  • are pregnant or plan to become pregnant. It is not known if MYOBLOC can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if MYOBLOC passes into breast milk.

Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Talk to your doctor before you take any new medicine after you receive MYOBLOC.

Using MYOBLOC with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received MYOBLOC in the past. Especially tell your doctor if you: have received any other botulinum toxin product in the last 4 months; have received injections of botulinum toxin such as BOTOX®, BOTOX® Cosmetic (onabotulinumtoxinA), DYSPORT® (abobotulinumtoxinA), or XEOMIN® (incobotulinumtoxinA) in the past. Be sure your doctor knows exactly which product you received; have recently received an antibiotic by injection; take muscle relaxants; take an allergy or cold medicine; take a sleep medicine.

What should I avoid while receiving MYOBLOC?

MYOBLOC may cause loss of strength or general muscle weakness or vision problems within hours to weeks of receiving MYOBLOC. If this happens, do not drive a car, operate machinery or do other dangerous activities.

What are the possible side effects of MYOBLOC?

MYOBLOC can cause serious side effects including:

  • allergic reactions. Symptoms of an allergic reaction to MYOBLOC may include: itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing, or trouble breathing, or if you get dizzy or faint.

The most common side effects of MYOBLOC in people with cervical dystonia include dry mouth; injection site discomfort or pain; trouble swallowing (dysphagia); headache.

The most common side effects of MYOBLOC in people with sialorrhea include dry mouth and trouble swallowing (dysphagia).

>These are not all the possible side effects of MYOBLOC. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see Medication Guide for additional information and talk with your healthcare provider.