For cervical dystonia in adults

MY KNOWLEDGE.

MY WAY.

MYOBLOC.

For cervical dystonia in adults

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Approved by the FDA 23 years ago, MYOBLOC® is a well-studied treatment for cervical dystonia (abnormal head position and neck pain). See why physicians consider MYOBLOC for their patients.

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The evidence

In clinical studies, MYOBLOC demonstrated:
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    Pain Relief*

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    Improvements in head and neck position by 4 weeks of treatment

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    12 to 16 weeks of 
    relief per injection

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    At least 3 years of relief with repeat injections (long-term unblinded study)

MYOBLOC achieved FDA approval based on 4 clinical studies, 2 Phase 3 (186 patients) and 2 Phase 2 (207 patients), that evaluated the efficacy, safety, and tolerability of MYOBLOC in adults with toxin A-responsive or toxin A-resistant cervical dystonia. These studies assessed the ability of MYOBLOC to reduce severity of abnormal head position, the effects of abnormal head position and pain on activities, and the severity and duration of dystonia pain, as measured by TWSTRS total and subscale scores.MYOBLOC was also evaluated in a long-term, unblinded (both the providers and patients know the treatment being given) study (145 patients), to assess the effect of subsequent injections on pain relief.

 

*In studies, adults treated with MYOBLOC had significant pain relief at 4 weeks after treatment.
Subsequent dosing should be determined by the patient’s individual response.
TWSTRS = Toronto Western Spasmodic Torticollis Rating Scale
 

A TRUSTED LEGACY SPANNING

23 years

MYOBLOC became the first FDA-approved neurotoxin for the treatment of cervical dystonia in adults on December 8, 2000. It remains the only FDA-approved type B option.

How MYOBLOC works

There are 2 types of botulinum toxin used to help treat cervical dystonia. Both block acetylcholine in different ways. MYOBLOC is a type B toxin that is administered right in your healthcare provider’s office and treatment takes only a few minutes.
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    MYOBLOC disables a protein that would typically trigger the release of excessive acetylcholine, which causes muscles to become tense and spasm.
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    When your healthcare provider injects MYOBLOC into affected muscles, it blocks the release of acetylcholine, allowing them to relax.
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    Over time, your healthcare provider will adjust the dose of MYOBLOC to achieve maximum pain relief and muscle spasm control. 

Most common MYOBLOC side effects

The most common side effects of MYOBLOC in people with cervical dystonia include dry mouth, trouble swallowing (dysphagia), injection site discomfort or pain, and headache.

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Use our questionnaire to talk with your healthcare provider about MYOBLOC

Our questionnaire can help guide the discussion. Fill it out, bring it to your next appointment, and talk about your symptoms with your healthcare provider.

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Financial assistance for MYOBLOC

Our payment support programs are available to patients who meet specific program eligibility requirements. Read about them and see other resources we have to support you.

A woman working at her laptop on her kitchen counter
A woman working at her laptop on her kitchen counter